• In recent years there has been growing interest regarding

  2019-05-07

  

  In recent years, there has been growing interest regarding the role of spliceosome machinery in neoplastic diseases following evidence of the involvement of splicing factor mutations in diverse cancers . (Serine-Arginine Splicing Factor 2) is a member of the serine/arginine (S/A) rich family pre-mRN

• Introduction The Space Shuttle has

  2019-05-07

  

  Introduction The Space Shuttle has been retired and the International Space Station (ISS) will be in use until 2020 (Fig. 1). Scientists and engineers are thinking about a mission to Mars in the future. Human exploration of space is at a turning point, and a number of questions about the future of

• br Conclusion br Conflicts of interest

  2019-05-06

  

  Conclusion Conflicts of interest Clinical case The worldwide estimated prevalence of cardiovascular implantable electronic device (CIED) infection is 1–2%. Prompt removal of infected devices ensures survival [1–4]. We report successful extraction of a lead from an infected CIED by using an

• Much previous work highlights the rapid increases in

  2019-05-06

  

  Much previous work highlights the rapid increases in DAH in the past decade, but in , Katherine Floyd and colleagues report that, in the case of tuberculosis, growth in domestic financing has been equally impressive. Their findings are convincing, especially in view of the fact that their study migh

• El texto tiene seis grandes secciones a

  2019-05-06

  

  El texto tiene seis grandes secciones Forskolin las que se suman el “propósito y los agradecimientos” y dos índices. En la introducción, León Frías problematiza la noción de , la cual agrupa un conjunto principalmente heterogéneo de películas; para el autor esta denominación se populariza a finales

• br Methods br Results br Discussion

  2019-05-06

  

  Methods Results Discussion Bisphosphonates reduce skeletal morbidity in patients with advanced cancers involving bone and have become a recommended component of the multidisciplinary treatment of MBD [1]. However, bone-health benefits have not generally translated into significantly improve

• The lead ECG and dimensional geometrical

  2019-05-06

  

  The 12-lead ECG and 2-dimensional geometrical maps for corrected RT interval difference and corrected Tp–e interval difference obtained by using 187-ch RIDM-ECG before and during the intravenous amiodarone infusion for representative cases are shown in Figs. 1 and 2 respectively. The mean value of Q

• br Conclusion br Conflicts of

  2019-05-06

  

  Conclusion Conflicts of interest Acknowledgments Case report A 56-year-old woman with prior history of dual-chamber permanent pacemaker (PPM) implantation (ELA Medical Symphony DR 2550, ELA Medical, Montrouge, France) for symptomatic complete Cyt 387 block presented to the Cardiac Rhyth

• Actualmente los movimientos sociales est n desarrollando

  2019-05-05

  

  Actualmente, los movimientos sociales están desarrollando ya una importante función de “representación expresiva”, y transmiten puntos de identificación en una sociedad fragmentada que impugna al Estado y retinoic acid la sociedad sobre la exclusión y las desigualdades existentes. Justamente, el seg

• br Universalismo cosmopolitismo y pol ticas

  2019-05-05

  

  Universalismo, cosmopolitismo y políticas culturales La conciencia universalista y el cosmopolitismo han sido productos de los movimientos y de los intercambios cada vez más acelerados de nuestro mundo. Desde las expansiones mercantiles y católicas del siglo xvi, los parámetros y los referentes a

• br Introduction Acute myeloid leukemia AML remains a

  2019-05-05

  

  Introduction Acute myeloid leukemia (AML) remains a hematologic malignancy with poor outcome and a high risk for relapse believed to be caused by the survival of leukemic stem cells (LSCs), which are responsible for disease repopulation following treatment [1]. This important implication of LSCs

• br Discussion Catheter ablation has played an

  2019-05-05

  

  Discussion Catheter ablation has played an increasingly important role in controlling VT episodes in patients with structural Dihydromyricetin disease who have an ICD [6–10]. LPs recorded at an endocardial ventricular site reflect slow conduction into a protected zone. Strategies for the success

• Complete surgical resection of the tumor at the

  2019-05-05

  

  Complete surgical resection of the tumor at the time of diagnosis is essential towards effective management of PPB. Unfortunately, a large cohort of patients present with an advance stage of disease where the tumor has grown to such an extent to invade surrounding vital structures, hindering the com

• Preclinical studies have shown that

  2019-05-05

  

  Preclinical studies have shown that adipocytes and MSCs play an important role in migration and dissemination of cancer pmsf [55,56]. Concerning osteosarcoma, one publication has reported that human MSCs injected through the caudal vein of mice bearing Saos-2- induced an increase in tumor volume ass

• diazoxide The beats with high amplitude J wave with short

  2019-05-04

  

  The beats with high-amplitude J wave with short preceding DIs induced low systolic blood pressure, indicating weak cardiac contractility due to decreased calcium influx through I and calcium release during ventricular systole. In contrast, the beats with low-amplitude J wave preceded by long DIs ind

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